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Alzheimer's Clinical Trials Consortium Down Syndrome

Alzheimer's Clinical Trials Consortium Down Syndrome

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Dr. Martin Sadowski, MD, PhD, DSci

April 17, 2026 by

Martin J. Sadowski, MD, PhD, DSci is a Tenured Professor of Neurology, Psychiatry, and Biochemistry and Molecular Pharmacology at the NYU Grossman School of Medicine and the Director of the Fisher Center Alzheimer’s Clinical Trials Program at NYU. Dr. Sadowski specializes in medical care of patients with Alzheimer’s disease and other forms of dementia and conducts translational research and clinical research on Alzheimer’s disease therapeutics.

Dr. Sadowski received his MD/PhD degree from the Medical University of Gdansk in Gdansk, Poland. He completed postdoctoral fellowship in experimental neuropathology under the mentorship of Dr. Henry M. Wisniewski in the New York State Institute for Basic Research on Staten Island, NY, and then residency in adult neurology at the NYU Medical Center in New York. Dr. Sadowski joined the faculty of the NYU School of Medicine in 2002.

Dr. Sadowski attends patients with mild cognitive impairment, Alzheimer’s disease, fronto-temporal dementia, and other age-related neurodegenerative diseases. He also leads the NYU Alzheimer’s Clinical Trial Program and is the Principal Investigator of the Laboratory for Alzheimer’s Disease Therapeutics within the Department of Neurology.

Research in Dr. Sadowski’s laboratory focuses on amyloid-beta metabolism, apolipoprotein E, and discovery of novel therapeutics for Alzheimer’s disease and prion diseases. His research has been supported by the funding from the National Institute on Aging, American Federation for Aging Research, Fisher Center for Alzheimer’s Research Foundation, Alzheimer’s Association, and private philanthropy.

Dr. Sadowski has been the recipient of the Markey’s Career Development Award, the Paul B. Beeson Career Development Award in Aging Research, and the NIA K02 Independent Scientist Award. He has authored over 130 papers in the field of Alzheimer’s disease, holds three U.S. patents on Alzheimer’s therapeutics, and has served on numerous NIH advisory panels.

Dr. Sadowski has been the Principal Investigator for over 40 Alzheimer’s clinical trials at the NYU Grossman School of Medicine and has served on Scientific Advisory Boards for the American Foundation for Aging Research, Eisai, Biogen, Eli Lilly, Genentech, and Glaxo-Smith-Kline, providing his expertise on the development of Alzheimer’s disease therapeutics.

Dr. Aimee Pierce, MD

April 17, 2026 by

Dr. Aimee Pierce is a geriatric neurologist focused on patient care and clinical research for people with Alzheimer’s disease and other forms of dementia. She is the Director of the Clinical Care and Therapeutics Program of the OHSU Layton Aging and Alzheimer’s Disease Center and has been the principal investigator of more than 20 clinical trials for Alzheimer’s disease prevention and treatment, in phases 2 and 3. In addition to pharmaceutical clinical trials, she is also focused on testing novel behavioral interventions for AD including cognitive and physical exercise, as well as the incorporation and validation of digital biomarkers into Alzheimer’s research. Finally, she has a focus on clinical trial recruitment and the research participant experience.

Marwan Noel Sabbagh MD, FAAN

August 5, 2025 by

Marwan Noel Sabbagh, MD, board certified neurologist and geriatric neurologist, has dedicated his career to finding a cure for Alzheimer’s and other age-related neurodegenerative diseases.

Dr. Sabbagh is a leading investigator for many prominent national Alzheimer’s treatment trials. Dr. Sabbagh is on the editorial board for Journal of Alzheimer’s Disease and Alzheimer’s and Dementia TRCI. He is editor-in-chief of Neurology and Therapy. He has authored and co-authored over 450 medical and scientific articles on Alzheimer’s research.

Dr. Sabbagh is the author of The Alzheimer’s Answer: Reduce Your Risk and Keep Your Brain Healthy, with foreword by Justice Sandra Day O’Connor, and of The Alzheimer’s Prevention Cookbook: 100 Recipes to Boost Brain Health. He has edited Palliative Care for Advanced Alzheimer’s and Dementia: Guidelines and Standards for Evidence Based Care and Geriatric Neurology, published in 2014 and Fighting for my Life: living in the shadow of Alzheimer’s disease in 2019 and Strong Heart, Sharp Mind published in 2022.

Dr. Sabbagh earned his undergraduate degree from the University of California, Berkeley and his medical degree from the University of Arizona in Tucson. He received his residency training in neurology at Baylor College of Medicine, Houston, Texas, and completed his fellowship in geriatric neurology and dementia at the University of California, San Diego School of Medicine, where he served on the faculty as assistant professor.

Before joining the faculty of the Barrow Neurological Institute, he was the Camille and Larry Ruvo Endowed Chair for Brain Health, the Director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas and the founding Principal Investigator of the NIH funded Nevada Exploratory Alzheimer’s Disease Research Center. From 2000-2015, he was the director of the Banner Sun Health Research Institute in Sun City AZ. From 2015-2018, he was the Karsten Solheim Endowed Chair for Alzheimer’s research at the Barrow Neurological Institute. Presently, in addition to being vice chair, he also serves as Associate Program Director for Research for the Neurology Residency

Charles Bernick, MD, MPH

August 5, 2025 by

Charles Bernick, MD, MPH, is Senior Director, Cognitive Disorders at the Cleveland Clinic Lou Ruvo Center for Brain Health. Dr. Bernick has been involved in the field of Alzheimer’s disease research and treatment for close to 40 years, beginning as the attending neurologist for the University of California, Davis Alzheimer’s Disease Diagnostic and Treatment Center. Dr. Bernick moved to Las Vegas in 1994 to join the University of Nevada School of Medicine and then joined the Cleveland Clinic Lou Ruvo Center for Brain Health in 2009. He has been involved in the clinical development of all the approved drugs for Alzheimer’s disease and has guided the Professional Fighters Brain Health study, a longitudinal cohort study of professional combatants aimed at understanding the effects of cumulative head trauma on brain structure and function.

He graduated summa cum laude from Rice University with a BA degree in history. He received his MD from University of Texas Southwestern, being elected to the medical honor society, alpha omega alpha. Dr. Bernick completed a neurology residency at the University of Miami, followed by a fellowship in neurology at the University of Arizona, and a Masters of Public Health at the University of Nevada, Las Vegas.

Anne-Sophie Rebillat, MD

March 13, 2024 by

Anne-Sophie Rebillat is a geriatrician. Within the Jérôme Lejeune Institute in Paris, she runs a clinic specialized in the management of age-related diseases for patients with Down syndrome. Her research interest is mainly focused on comorbidities of cognitive functioning with aging in people with Down syndrome, e.g. Alzheimer’s disease and Obstructive Sleep Apnea.

Sean Kennelly, MD

March 13, 2024 by

Professor Kennelly is a consultant physician in geriatric and stroke medicine in Tallaght University Hospital (TUH) and Clinical Associate Professor of Medical Gerontology in Trinity College. He is Director of the Institute for Memory and Cognition, and the Cognitive Clinical Trials Unit in Tallaght University Hospital, Dublin. He is clinical director of the National Intellectual Disability Memory Service in TUH. He is lead-PI and chair of Dementia Research Network Ireland (DRNI), and co-lead investigator on Dementia Trials Ireland, a national clinical trials network. A fellow of the Royal College of Physicians in London & Ireland, he has extensively published in his main research areas of ageing, brain health and dementia. He has served as chief and principal investigator on several international clinical trials in early-stage Alzheimer’s disease. He is principle investigator and lead-clinical advisor on several industry collaborations investigating novel applications of digital gait and speech biomarkers in detection of cognitive decline. He is a member of the clinical and research advisory panel for the Alzheimer’s Society Ireland and a principal investigator in the Trinity College Institute of Neuroscience. He is a faculty member for the Global Brain Health Institute in Trinity College Dublin.

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